• Murat Akova, Ankara, Turkey
  • Maiken Arendrup, Copenhagen, Denmark
  • Sujata Bhavnani, Schenectady, NY, United States
  • Marco Cavaleri, London, United Kingdom
  • Herman Goossens, Edegem, Belgium
  • David Hooper, Boston, MA, United States
  • William Hope, Liverpool, United Kingdom
  • John Rex, Wellesley, MA, United States
  • Jesús Rodríguez Baño, Seville, Spain
  • Keith Rodvold, Chicago, IL, United States
  • Michael Sharland, London, United Kingdom
  • Judith Steenbergen, Boston, MA, United States
  • Sumathi Nambiar, Washington D.C., United States
Antimicrobial drug resistance remains a pressing public health problem. There has been a resurgence in interest in tackling AMR. This conference focusses on the development of new antimicrobial agents for AMR. It is a multidisciplinary meeting that involves basic scientists, clinical academics, regulatory bodies, funding bodies and the pharmaceutical industry. Its scope stretches from chemistry to clinical development, from neonates to adults, from bacteria to fungi – all with a global perspective. The meeting is practical, interactive with plenty of time for networking. We will happily accept original data for poster and platform presentations. We are also especially interested in supporting young investigators and researchers from low to middle income countries.

Drug development for AMR is a rapidly moving field. The stakes are high. A difficult riskbenefit balance must be struck. There are relatively few new classes of antibiotics and each requires highly skilled and experienced investigators to ensure these compounds reach patients. This meeting is the forum where those issues are discussed and debated.

Contact Person (Scientific Programme)

Administrative Secretariat

Venue Info

Event Map
Venue Details
Intercontinental Lisbon
R. Castilho 149, 1099-024 Lisbon
An exciting and engaging 4-day programme is planned, with a faculty of experts scheduled to present on a variety of topics relating to antimicrobial resistance, new drug development, and stewardship strategies.

Tuesday, 4 September 2018

08:30 - 09:30
Opening Talks and Welcome
09:30 - 10:00
Coffee Break
10:00 - 12:00
Bootcamp: Medicinal Chemistry
Chairperson(s): John H. Griffin
Chairperson(s): Heinz Moser
10:00 - 10:30
Drug-Likeness: Physicochemical Properties in Small-Molecule Drug Discovery
Speaker(s): Andrea Decker
10:30 - 11:00
Drug Discovery of Antibiotics: The Importance of Physicochemical Properties
Speaker(s): Heinz Moser
11:00 - 11:30
Emerging Artificial Intelligence Approaches in Drug Discovery and their Application to Antibiotic Design
Speaker(s): John H. Griffin
11:30 - 12:00
Roundtable Discussion
Speaker(s): Andrea Decker
Speaker(s): John H. Griffin
Speaker(s): Heinz Moser
Speaker(s): John H. Rex
12:00 - 13:00
Lunch and Poster Viewing
13:00 - 15:00
Bootcamp: Preclinical Toxicology
Chairperson(s): Ursula Theuretzbacher
13:00 - 13:30
Pitfalls in Preclinical Development from the Regulatory Perspective (FDA)
Speaker(s): Terry Miller
13:30 - 14:00
When the minimum is not enough: from the regulatory perspective: (EMA)
Speaker(s): To Be Advised
14:00 - 14:30
Making Safety a Part of Drug Design
Speaker(s): Claire Sadler
14:30 - 15:00
Real life story of unexpected toxicity - Lessons to learn
Speaker(s): Ryan Cirz
15:00 - 15:30
Coffee Break
15:30 - 17:00
Regulatory Roundtable
Chairperson(s): Marco Cavaleri
Chairperson(s): Sumathi Nambiar
Speaker(s): Edward Cox
Speaker(s): Junko Sato
Speaker(s): Ming Zhao
16:10 - 16:30
Coffee Break
17:00 - 17:15
Short Break
17:15 - 20:00
Welcome Cocktail Function

Wednesday, 5 September 2018

08:30 - 11:00
State of the Art Lecture: New Antibacterial Agents
Chairperson(s): William Hope
Chairperson(s): Keith Rodvold
08:30 - 08:55
Speaker(s): Roger M. Echols
08:55 - 09:20
Relebactam + Imipenem/Cilastatin
Speaker(s): Amanda Paschke
09:20 - 09:45
Speaker(s): Larry Tsai
09:45 - 10:10
Speaker(s): Evan Tzanis
10:10 - 10:35
Speaker(s): David Huang
10:35 - 11:00
Speaker(s): Steven Gelone
11:00 - 11:30
Coffee Break
11:30 - 12:00
Young Investigator Lecture: Clinical trial design, clinical endpoints, recruitment issues for clinical trials in AMR
Chairperson(s): Sumathi Nambiar
Chairperson(s): Jesús Rodríguez-Baño
Speaker(s): Marlieke de Kraker
12:00 - 13:00
Lunch and Poster Viewing
13:30 - 14:30
Plenary: Preparing for the Black Swans of resistance
Chairperson(s): Murat Akova
Speaker(s): David Livermore
14:30 - 14:40
Short Break
14:40 - 16:10
Rapid Diagnostic Testing for AMR
Chairperson(s): Maiken Cavling Arendrup
Chairperson(s): Judith Steenbergen
14:40 - 15:10
Next Generation AST: Rapid Results and Expanded Antibiotic Menus
Speaker(s): Eric Stern
15:10 - 15:40
Streamlining antibacterial clinical development through the use of rapid diagnostics
Speaker(s): Andrew Tomaras
15:40 - 16:10
Clinical Applications: Implementation and clinical management
Speaker(s): Rosanna Peeling
16:10 - 16:30
Coffee Break
16:30 - 18:00
Pharmacodynamics of Adjunctive Therapies: Paradigm Changing Therapies
Chairperson(s): Sujata Bhavnani
Chairperson(s): Marco Cavaleri
16:30 - 16:48
Regulatory Perspectives
Speaker(s): Marco Cavaleri
16:48 - 17:06
Antibiotic Potentiators
Speaker(s): Troy Lister
17:06 - 17:24
Bacterial Growth Rate Modulators
Speaker(s): Paul Ambrose
17:24 - 17:42
Monoclonal Antibodies
Speaker(s): Rene L Russo
17:42 - 18:00
Phage Therapy
Speaker(s): Harald Brüssow

Thursday, 6 September 2018

08:30 - 10:30
Building the Evidence Base to Inform AMR-Related Decision-Making
Chairperson(s): John H. Rex
08:30 - 09:00
Policy overview: why is surveillance important and what do policy makers need?
Speaker(s): Jeremy Knox
09:00 - 09:30
Surveillance Landscape: overview of current programmes and initiatives
Speaker(s): Sharon Peacock
09:30 - 10:00
Surveillance in pharma: a case-study for data sharing.
Speaker(s): Barry Cookson
10:00 - 10:30
Roundtable Discussion
Speaker(s): Barry Cookson
Speaker(s): Jeremy Knox
Speaker(s): Kevin Krause
Speaker(s): Sharon Peacock
Speaker(s): Carmem Lucia Pessoa-Silva
Speaker(s): Didem Torumkuney
10:30 - 11:00
Coffee Break
11:00 - 11:30
Young Investigator Lecture: Metallobetalactamases (Epidemiology, Drug Design, Diagnosis and Treatment)
Chairperson(s): David C. Hooper
Chairperson(s): David Livermore
Speaker(s): Sara Boyd
11:30 - 12:30
Plenary: Stewardship of New and Last-Resort Antibiotics in LIMCs - Balancing Access and Control?
Chairperson(s): David C. Hooper
Speaker(s): Marc Mendelson
12:30 - 14:00
Lunch and Poster Viewing
14:00 - 15:30
State of the Art Lecture: Antifungal agents and Antifungal Drug Development
Chairperson(s): Maiken Cavling Arendrup
Chairperson(s): Sumathi Nambiar
14:00 - 14:30
5 unmet medical needs for antifungal chemotherapy
Speaker(s): David W. Denning
14:30 - 15:00
Review of the antifungal pipeline
Speaker(s): John R. Perfect
15:00 - 15:30
Design and conduct of Phase II and III clinical trials for new antifungal agents
Speaker(s): Peter Pappas
15:30 - 16:00
Coffee Break
16:00 - 17:30
Approaches to Tackle AMR in Low-to-Middle Income Countries
Chairperson(s): Marc Mendelson
16:00 - 16:30
Challenges and barriers to optimal dosing of old drugs for the management of common bacterial infections in LMICs
Speaker(s): Johan Willem Mouton
16:30 - 17:00
What is the evidence base for combinations of old antibiotics for the treatment of MDR bacteria?
Speaker(s): Evelina Tacconelli
17:00 - 17:30
Do we need new financial models to secure supply of old antibiotics?
Speaker(s): Christine Årdal

Friday, 7 September 2018

08:30 - 10:00
Breakpoints for new Antimicrobial Agents
Chairperson(s): Maiken Cavling Arendrup
08:30 - 08:45
The role of breakpoint committees in the development of new antibacterial agents - EUCAST
Speaker(s): Christian Giske
08:45 - 09:00
The role of breakpoint committees in the development of new antibacterial agents - US perspective
Speaker(s): Jean Patel
09:00 - 09:15
The role of breakpoint committees in the development of new antifungal agents
Speaker(s): Shawn R. Lockhart
09:15 - 09:30
How to define wild type distributions of target organisms
Speaker(s): Maiken Cavling Arendrup
10:00 - 10:30
Coffee Break
10:30 - 11:00
Young Investigator Lecture: Pharmacokinetics/Pharmacodynamics
Chairperson(s): George Drusano
Chairperson(s): Alisdair MacGowan
Speaker(s): Nik Onufrak
11:00 - 12:00
Plenary: Days of Future Passed: What is Needed To Discover and Develop New Antimicrobials?
Chairperson(s): Murat Akova
Speaker(s): Michael Dudley
12:00 - 13:30
Lunch and Poster Viewing
13:30 - 15:00
Clinical Trial Design for AMR
Chairperson(s): Herman Goossens
Chairperson(s): Jesús Rodríguez-Baño
13:30 - 13:50
Adaptative trials with new antibiotics
Speaker(s): Cornelis H. Van Werkhoven
13:50 - 14:10
 Challenges for pathogen-target trials
Speaker(s): Jesús Rodríguez-Baño
14:10 - 14:30
Advanced observational studies for MDR pathogens: useful or confounding?
Speaker(s): Mical Paul
14:30 - 14:50
Challenges of trials with new antibiotics: the view of the industry
Speaker(s): John Tomayko
15:00 - 15:30
Coffee Break
15:30 - 17:00
Drug Discovery in Academia
Chairperson(s): David C. Hooper
15:30 - 16:00
Drugs from bugs of bugs – An unexpected source and collaboration
Speaker(s): David Andes
16:00 - 16:30
Discovering antibiotic adjuvants to extend the life of existing drugs
Speaker(s): Gerry D Wright
16:30 - 17:00
Overview of techniques used in drug discovery
Speaker(s): Ian Gilbert

There are several options to transfer from the Airport to the hotel

By taxi: 15-20 minutes, the cost is around €15-17.
By bus: (Aerobus) to Praça Marquês de Pombal, the nearest stop to the hotel then a 10 minute walk (uphill).
By metro: Aeroporto station until the end of red line (São Sebastião station), then a 10 minute walk.

The hotel can also arrange a private transfer with an English speaking driver : 

Car ( Mercedes E Class - space for 3 people and 3 bags) - Price : €50
Mini-van ( Mercedes V Class - space for 6 people and 6 bags) - Price : €80

Private transfers will have to be booked with the hotel directly ( + 351 213 818 700 )
If you are an ASM member, please kindly send the membership proof to lisbon2018@escmid.org in order to be given the membership discount.
Cancellation Policy (Terms and Conditions): Over 30 days before the start of the course - 60% of the amount will be charged. Less than 30 days before the start of the course - 100% of the amount will be charged. No charges apply for a suitable, qualified substitute participant. The organizers reserve the right to cancel the course up to two weeks before the start date. A full refund of the course fees will be allowed, but the organizers cannot be held responsible for any other costs incurred (transports, hotels, etc.).
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Share and discuss your research with colleagues from around the world. Abstracts can be submitted from 1 March - 22 June 2018.
Please download the template and submit it by email to: lisbon2018@escmid.org
If you have any questions or need any assistance, please do not hesitate to contact us at lisbon2018@escmid.org

For more detailed information, please download the flyer HERE and the poster HERE.